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Figure 1: The scheme of superparamagnetic iron oxide nanoparticle (SPIONs) conjugation to the C595 monoclonal antibody (mAb): (a) Functionalization of SPIO-CLD-NH2 with sulfo-SMCC and (b) conjugation of thiolated antibody to maleimide functionalized SPIONs

Figure 1: The scheme of superparamagnetic iron oxide nanoparticle (SPIONs) conjugation to the C595 monoclonal antibody (mAb): (a) Functionalization of SPIO-CLD-NH<sub>2</sub> with sulfo-SMCC and (b) conjugation of thiolated antibody to maleimide functionalized SPIONs