Journal of Medical Physics
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Year : 2022  |  Volume : 47  |  Issue : 1  |  Page : 109-113

Embryo/Fetus doses from 18F-fludeoxyglucose radiopharmaceutical in positron emission tomography/computed tomography

1 Department of Electrical and Electronics Engineering, Faculty of Engineering and Architecture, Nisantasi University, Istanbul, Turkey
2 Department of Nuclear Medicine, Faculty of Cerrahpasa Medical, Istanbul University-Cerrahpasa, Istanbul, Turkey

Correspondence Address:
Nazenin Ipek Isikci
Department of Computer Engineering, Faculty of Engineering and Architecture, Nisantasi University, Sarıyer, Istanbul
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jmp.jmp_115_21

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Aim: The embryo/fetus may be accidentally exposed to ionizing radiation. The aim of this study is to calculate embryo/fetus doses in pregnant women who underwent F-18 fludeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) scan. Materials and Methods: Between June 2015 and June 2021, 15 pregnant women underwent F-18 FDG PET/CT applied to the Genetic Research Center (GETAM). The OLINDA/EXM package program was used for internal radiation dosimetry according to the Medical Internal Radiation Dose scheme. FetDose V4 computer software was used to compute the embryo/fetus absorbed dose from CT scan. Results: The amount of the injected F-18 FDG activity to patients varied between 333 and 555 MBq. The mean embryo/fetal dose from F-18 FDG was 7.2 ± 2.8 mGy. In addition, the CT component dose to the embryo/fetus dose ranged from 8.5 to 16 mGy with a mean of 12.14 ± 2.05. Conclusions: The embryo/fetus dose from F-18 FDG PET/CT was <15 mGy, however, questioning the women's childbearing prior to scintigraphy is the first-line strategy to avoid accidental radiation exposure and stochastic risks.

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