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Modern medical imaging is a multidisciplinary field encompassing various fields such as anatomy, atomic and nuclear physics, solid state physics, electronics, instrumentation and computer engineering. There have been a number of advances in x-ray imaging both from the point of view of equipment as well as those of detector systems. This paper reviews some of the important developments. The principles involved in some of the new x-ray equipment such as AMBER and low scatter digital x-ray systems are discussed. Stress is laid on computed radiography (CR) using storage phosphor (SP) plate since this technique has provided a replacement for conventional screen-film system, with its attendant advantages. Physics of photostimulated luminescence (PSL) and CR instrumentation are described. CR has been compared with screen-film system. Recent developments in digital radiography (DR) are also presented. The applications of computer in these fields are outlined. The paper concludes with a brief discussion on developments in CT scanners and the importance of quality assurance.