Journal of Medical Physics
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Year : 1995  |  Volume : 20  |  Issue : 2  |  Page : 26-30

The Role Of Extrapolated Response Dose Concept In HBI Treatments Of Disseminated Painful Osseous Metastases

Correspondence Address:
M S Belliappa

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Hemibody irradiation (HBI) has emerged as an efficient and effective treatment for the palliation of pain in patients with symptomatic widespread cancer. The rational for such an unconventional radiation delivery is to try to achieve effective pain palliation to large affected body areas with prompt efficiency and minimal inconvenience to terminal cancer patients. In this report a prospective study is undertaken as to the existence of a correlation between ERD versus response rate in a series of patients with disseminated painful osseous metastases with megavoltage HBI treatments. Correlation of ERD with response rate was excellent. There was a sharp increase in response rate from ERD of 13 Gy onwards (p value < 0.05). From our results it is suggested that in the HBI treatments of disseminated painful osseous metastases ERD value'l3 Gy as the minimum for a favourable response rate as per the treatment schedule that we have used.

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