Journal of Medical Physics
 Home | Search | Ahead of print | Current Issue | Archives | Instructions | Subscription | Login  The official journal of AMPI, IOMP and AFOMP      
 Users online: 267  Home  EMail this page Print this page Decrease font size Default font size Increase font size 
Year : 1992  |  Volume : 17  |  Issue : 2  |  Page : 10-12

Extrapolated Response Dose (ERD) AS A Potential Guide In The Management Of Carcinoma Of Uterine Cervix

Correspondence Address:
Sanjay S Supe

Login to access the Email id

Source of Support: None, Conflict of Interest: None

Rights and PermissionsRights and Permissions

A retrospective analysis of 291 patients with cancer of the uterine cervix treated with a combination of external and intracavitary radiotherapy was carried out. Patients were treated with external radiotherapy dose of 45 Gy in 20 fractions, 5 fractions per week or 42 Gy in 14 fractions, 3 fractions per week. For brachytherapy the total dose was 24 to 32 Gy at a dose rate of'1. 4 to 2.2 gy per hour. Treatment results in terms of response, survival, recurrence and complication were correlated with total Extrapolated Response Dose (ERD) values for point A (ERDTA) and for rectum (ERDT,). ERDTA values did not correlate with response, recurrence and survival rates (p value >0.05). ERDTA values correlated well with rectal complication rate (p value >0.025). Lack of correlation was observed between ERDT, with rectal complication rate (p value >0.1). In order to limit Grade II and Ill rectal complications to acceptable level, in combined external and intracavitary treatments, ERDTA value of less than 93 is suggested.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded74    
    Comments [Add]    

Recommend this journal