Journal of Medical Physics
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Year : 1990  |  Volume : 15  |  Issue : 2  |  Page : 135-137

Effectiveness Of Chemotherapy On Secondaries In Liver As Evidenced By Scan Changes

Correspondence Address:
K K Agarawal

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The present study observes the effect of Chemotherapy on secondaries in liver of breast carcinoma, proving the role of liver scintigraphy as an objective tool. During a period of two years liver scintigraphy was done in 2566 patients of whom 592 patients were cases of carcinoma breast. Out of these 592 patients 81 patients showed secondaries in liver confirmed by hepatic scintigraphy. But only 14 patients of secondaries in liver of breast carcinoma, received chemotherapy and were also available for fallow up for post chemotherapy liver scan. Consequently a comparison between pre and post chemotherapy liver scan showed the effect of chemotherapy. Fourteen patients GP A (7 pts) was given classical CMF (Cyclophosphamide, Methotrexate and 5 Flurouracil) regime and GP B (7 pts) was given a combination chemotherapy consisting of more than 3 drugs. In GP A, 4 out of 7 pts (57.14%) and in GP 8, 6 out of 7 pts (85.7%) showed the improvement. This suggests that Chemotherapy is effective in metastatic liver of Ca breast and multiple drug combination therapy is more effective than the classical CMF regime. Further liver scintigraphy is a useful indicator for assessing the response

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